Genetic counselors' (GC) knowledge, awareness, understanding of clinical next-generation sequencing (NGS) genomic testing
作者： P.M. Boland , K. Ruth , J.M. Matro , K.L. Rainey , C.Y. Fang
DOI: 10.1111/CGE.12555
关键词:
摘要: Genomic tests are increasingly complex, less expensive, and more widely available with the advent of next-generation sequencing (NGS). We assessed knowledge perceptions among genetic counselors pertaining to NGS genomic testing via an online survey. Associations between selected characteristics were examined. Recent education on was common, but practical experience limited. Perceived understanding clinical modest, specifically concerning tumor testing. Greater perceived correlated time spent in cancer-related counseling, exposure testing, NGS-focused education. Substantial disagreement about role counseling for tumor-based seen. Finally, a majority agreed need supporting this approach optimizing implementation.
sci-hub.se 参考文章(17)
John A. Robertson, Consent and privacy in pharmacogenetic testing Nature Genetics. ,vol. 28, pp. 207- 209 ,(2001) , 10.1038/90032
R. Drmanac, A. B. Sparks, M. J. Callow, A. L. Halpern, N. L. Burns, B. G. Kermani, P. Carnevali, I. Nazarenko, G. B. Nilsen, G. Yeung, F. Dahl, A. Fernandez, B. Staker, K. P. Pant, J. Baccash, A. P. Borcherding, A. Brownley, R. Cedeno, L. Chen, D. Chernikoff, A. Cheung, R. Chirita, B. Curson, J. C. Ebert, C. R. Hacker, R. Hartlage, B. Hauser, S. Huang, Y. Jiang, V. Karpinchyk, M. Koenig, C. Kong, T. Landers, C. Le, J. Liu, C. E. McBride, M. Morenzoni, R. E. Morey, K. Mutch, H. Perazich, K. Perry, B. A. Peters, J. Peterson, C. L. Pethiyagoda, K. Pothuraju, C. Richter, A. M. Rosenbaum, S. Roy, J. Shafto, U. Sharanhovich, K. W. Shannon, C. G. Sheppy, M. Sun, J. V. Thakuria, A. Tran, D. Vu, A. W. Zaranek, X. Wu, S. Drmanac, A. R. Oliphant, W. C. Banyai, B. Martin, D. G. Ballinger, G. M. Church, C. A. Reid, Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays Science. ,vol. 327, pp. 78- 81 ,(2010) , 10.1126/SCIENCE.1181498
D Gurwitz, J E Lunshof, G Dedoussis, C S Flordellis, U Fuhr, J Kirchheiner, J Licinio, A Llerena, V G Manolopoulos, L J Sheffield, G Siest, F Torricelli, V Vasiliou, S Wong, Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics Journal. ,vol. 5, pp. 221- 225 ,(2005) , 10.1038/SJ.TPJ.6500312
Andrew D. Feld, Informed consent: not just for procedures anymore. The American Journal of Gastroenterology. ,vol. 99, pp. 977- 980 ,(2004) , 10.1111/J.1572-0241.2004.40520.X
AR Bradbury, L Patrick-Miller, D Fetzer, B Egleston, SA Cummings, A Forman, L Bealin, C Peterson, M Corbman, J O'Connell, MB Daly, Genetic counselor opinions of, and experiences with telephone communication of BRCA1/2 test results Clinical Genetics. ,vol. 79, pp. 125- 131 ,(2011) , 10.1111/J.1399-0004.2010.01540.X
Rebecca Sutphen, Barbara Davila, Heather Shappell, Tricia Holtje, Susan Vadaparampil, Sue Friedman, Michele Toscano, Joanne Armstrong, Real world experience with cancer genetic counseling via telephone Familial Cancer. ,vol. 9, pp. 681- 689 ,(2010) , 10.1007/S10689-010-9369-Y
Susanne B. Haga, Genevieve Tindall, Julianne M. O'Daniel, Public Perspectives About Pharmacogenetic Testing and Managing Ancillary Findings Genetic Testing and Molecular Biomarkers. ,vol. 16, pp. 193- 197 ,(2012) , 10.1089/GTMB.2011.0118
K.E. Ormond, S. Banuvar, A. Daly, M. Iris, J. Minogue, S. Elias, Information preferences of high literacy pregnant women regarding informed consent models for genetic carrier screening. Patient Education and Counseling. ,vol. 75, pp. 244- 250 ,(2009) , 10.1016/J.PEC.2008.09.020
ACOG Committee Opinion No. 410: Ethical issues in genetic testing. Obstetrics & Gynecology. ,vol. 111, pp. 1495- 1502 ,(2008) , 10.1097/AOG.0B013E31817D252F
Monica D. Nardini, Anne L. Matthews, Shawn E. McCandless, Larisa Baumanis, Aaron J. Goldenberg, Genomic Counseling in the Newborn Period: Experiences and Views of Genetic Counselors Journal of Genetic Counseling. ,vol. 23, pp. 506- 515 ,(2014) , 10.1007/S10897-014-9706-7