The Role of Cation-Activated ATPases in Transmitter Release from the Rat Iris

摘要: Release of noradrenaline (NA) from isolated rat iris during perfusion in K+-free medium was confirmed. Direct biochemical measurement different cation-activated ATPases did not reveal any definite relationship between Na+K+ ATPase and NA release. A significant increase Ca++Mg++ activity found on termination release obtained by reintroduction K+ to the medium. Criticism model for studying enzymatic control transmitter under physiological conditions is presented. It suggested that removal intracellular Ca++ ions a calcium pump directly associated with