TiCl4/Et3N-Mediated Condensation of Acetate and Formate Esters: Direct Access to β-Alkoxy- and β-Aryloxyacrylates
作者： José María Álvarez-Calero , Zacarías D. Jorge , Guillermo M. Massanet
DOI: 10.1021/ACS.ORGLETT.6B03233
关键词:
摘要: A methodology to build (E)-β-alkoxy- and (E)-β-aryloxyacrylate moieties from acetate formate esters promoted by the TiCl4/Et3N system is presented. The reaction compatible with a broad range of structural skeletons elapses through an unusual condensation pathway. Taking into account obtained results, we propose plausible mechanism involving bimetallic titanium intermediate for this type transformation.
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