Nomogram to Predict Survival of Patients With Recurrence of Hepatocellular Carcinoma After Surgery.

摘要: Background & Aims We aimed to establish and validate a nomogram predict survival at 2 5 years after recurrence of hepatocellular carcinoma (HCC) in patients who have undergone curative resection. Methods developed using data from training cohort 638 (most with hepatitis B virus infection) HCC resection Sun Yat-sen University Cancer Center, Guangzhou, China 2007 through 2013. The median follow-up time was 39.7 months. Patients were evaluated every 3–4 months for the first 3–6 thereafter. based on variables independently associated recurrence, including antiviral treatment; albumin-bilirubin grade alpha-fetoprotein level recurrence; primary size, site, number recurrences; treatment recurrence. validated an independent internal 213 treated same institution external 127 other centers China, 2002 2009. predictive accuracy measured Harrell's concordance index (C index) compared Barcelona Clinic Liver staging system Results Our predicted C-index 0.797 (95% CI, 0.765–0.830)—greater than that (C-index score, 0.713; 95% 0.680–0.745) ( P Conclusions determine probability survival, different points, infection), it internally externally.