Is cholecystectomy effective treatment for symptomatic gallstones? Clinical outcome after long-term follow-up.

作者: K Sivaniah , N West , G P Gui , C V Cheruvu , A G Fiennes

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摘要: The expectation that cholecystectomy is effective treatment for symptomatic gallstones not always achieved in surgical practice. impact of on the relief gastrointestinal symptoms was evaluated 92 patients followed up after surgery a mean 31.1 months (range 12-83 months). Abdominal pain continued to be present, or arose de novo, 28 (30.4%) patients. Pain-free outcome associated with preoperative clinical diagnosis biliary colic, fatty food intolerance, and thick-walled gallbladder ultrasound (P = 0.02). Logistic regression gallbladder, elevated gamma-glutamyl transpetidase, body mass index < 26, fat normal bowel habit good postoperative results 0.001). Application each these five factors failed predict long-term pain-free cholecystectomy. bloating 0.03), dyspepsia 0.001), heartburn 0.007), intolerance nausea 0.001) vomiting were significantly improved cholecystectomy, but diarrhoea, constipation excessive flatus not. Outcome benefit ratios confirmed (0.96), (0.87), (0.67), (0.57) (0.51) relieved by surgery. Cholecystectomy compared matched control group, suggesting remains gold standard gallstones.

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