Clinical presentation and monitoring of lupus nephritis.

摘要: The diversity of clinical presentations lupus nephritis parallel the pathologic lesions seen in kidneys patients with SLE. Renal manifestations range from asymptomatic hematuria or proteinuria to overt nephritic and nephrotic syndromes, rapidly progressive glomerulonephritis, chronic renal failure. Subclinical nephropathy both during presentation monitoring disease activity is frequently missed because notorious unreliability routine screening urinalyses performed high-throughput pathology laboratories. Requisitions for urine microscopy should be flagged special attention at risk nephritis. Depression classic complement pathway components high titers anti-DNA, anti-nucleosome, anti-Clq antibodies identify are increased involvement flares Several damage indexes available, but they mostly used research setting none has achieved wide use standard practice.