The sensitivity of fish brain atpases to ogranochlorine acaricides

摘要: Abstract Several chlorinated hydrocarbon pesticides, considered to be specific acaricides, were shown in vitro inhibitors of the ATPase enzyme system from blue gill fish brain homogenates. Mitochondrial (oligomycin-sensitive) Mg2+ATPase was inhibited by each bridged biphenyl compound (ovex, chlorberside, chlorobenzilate, 4,4′-dichloro-a-methylbenzhydrol, and 2,4-dichlorophenyl benzenesulfonate). Moreover, these compounds relatively ineffective on Na+-K+ATPase oligomycin-insensitive Mg2+ATPase. In contrast, decachlorobi-2, 4-cyclopentadien-1-yl, a bicyclic pentadienyl compound, An alkyl aryl sulfite, 2-(p-tert-butyl-phenoxy)-1-methylethyl 2-chloroethyl system. vivo correlation, based upon behavior mites, between effect acaricidal activity.