In vitro disruption of ATP dependent active transport following treatment with aldrin and its epoxy analog dieldrin in a fresh water teleost, Labeo rohita.
作者： S.R. Verma , A.K. Gupta , S.K. Bansal , R.C. Dalela
DOI: 10.1016/S0300-483X(78)91189-7
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摘要: Summary Tissue homogenates of brain, gill, liver and kidney Labeo rohita were subjected in vitro to the various concentrations as 5.00, 1.66, 0.55, 0.18 0.06 μM 2 organochlorine pesticides aldrin dieldrin disruption ATP dependent active transport (involving ATPase) was studied. The inhibition total ATPase, Mg 2+ Na + , K -dependent ATPases by both quite similar there an increased with concentration toxicant, however, at lowest stimulation observed all tissues except gill ATPase where insignificant after treatment. Inhibition system noted maximum brain followed experimental fish, however each tissue treatment than that Therefore, action these might be related ability compounds alter cellular membrane configuration binding lipid portion thus blocking movement substances transport.
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