摘要: … As hitting multiple targets in restraint is perhaps more viable strategy rather than single target, this review, outlines the most germane multiple target agents of synthetic and natural …
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Khosrow Kashfi, Anti-inflammatory agents as cancer therapeutics. Advances in pharmacology (San Diego). ,vol. 57, pp. 31- 89 ,(2009) , 10.1016/S1054-3589(08)57002-5
Jerauld S Skotnicki, Jeremy I Levin, Martin J DiGrandi, Design strategies for the identification of MMP-13 and Tace inhibitors. Current Opinion in Drug Discovery & Development. ,vol. 6, pp. 742- 759 ,(2003)
Anti-inflammatory drug discovery Royal Society of Chemistry. ,(2012) , 10.1039/9781849735346
Geetha Mathew, M. K. Unnikrishnan, Multi-target drugs to address multiple checkpoints in complex inflammatory pathologies: evolutionary cues for novel “first-in-class” anti-inflammatory drug candidates: a reviewer’s perspective Inflammation Research. ,vol. 64, pp. 747- 752 ,(2015) , 10.1007/S00011-015-0851-8
Greenwald P, Sinha R, Anderson De, McDonald Ss, Cancer Risk and Diet in India Journal of Postgraduate Medicine. ,vol. 49, pp. 222- 228 ,(2003)
O. Rådmark, B. Samuelsson, Microsomal prostaglandin E synthase‐1 and 5‐lipoxygenase: potential drug targets in cancer Journal of Internal Medicine. ,vol. 268, pp. 5- 14 ,(2010) , 10.1111/J.1365-2796.2010.02246.X
Alan Talevi, Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective Frontiers in Pharmacology. ,vol. 6, pp. 205- 205 ,(2015) , 10.3389/FPHAR.2015.00205
Simon Frantz, Pharma faces major challenges after a year of failures and heated battles. Nature Reviews Drug Discovery. ,vol. 6, pp. 5- 7 ,(2007) , 10.1038/NRD2230
Fiorucci Stefano, Eleonora Distrutti, Cyclo-Oxygenase (COX) Inhibiting Nitric Oxide Donating (CINODs) Drugs: A Review of Their Current Status Current Topics in Medicinal Chemistry. ,vol. 7, pp. 277- 282 ,(2007) , 10.2174/156802607779941350
Debashis Singh, Merck withdraws arthritis drug worldwide. BMJ. ,vol. 329, pp. 816- 816 ,(2004) , 10.1136/BMJ.329.7470.816-A