Selective targeting of cancer cells using synthetic peptides.

摘要: To establish efficient and reliable therapeutic delivery into cancer cells, a number of agents concepts have been investigated in the recent years. Among many improvements targeted controlled therapeutics, cell-targeting peptides emerged as most valuable non-immunogenic approach to target cells. Peptides can be incorporated multicomponent gene-delivery complexes for cell-specific targeting. In contrast larger molecules such monoclonal antibodies, an excellent tumor penetration, which make them ideal carriers therapeutics site primary distant metastatic sites. Here we give update on progress made during last two years identification potential specific synthetic targeting peptides.