Histological pattern of benign breast disease as a risk factor for invasive breast cancer.

摘要: Morphological criteria for histologic diagnosis of both typical and atypical breast epithelial hyperplasias have recently been thoroughly reviewed. Typical hyperplasia ranges from mild to florid is characterized by a lack cytologic atypia. Atypical (AH) borderline lesion between carcinoma in situ. AH represents the most important histopathologic predictor future cancer (BC) according case-control study we carried out cohort women previously treated histologically confirmed benign disease (BBD). The use defined categories order predict BC risk depends on utilization strict uniform diagnostic that are currently far being widely accepted as shown studies inter-observer variability among pathologists. Further needed evaluate reproducibility assess with different BBD types.