STUDIES ON ARTIFICIAL ANTIGENS : III. THE GENETIC CONTROL OF THE IMMUNE RESPONSE TO HAPTEN-POLY-L-LYSINE CONJUGATES IN GUINEA PIGS

作者: Bernard B. Levine , Antonio Ojeda , Baruj Benacerraf

DOI: 10.1084/JEM.118.6.953

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摘要: The genetic transmission of the capacity to develop an immune response hapten-polylysine conjugates was studied in guinea pigs. 82 per cent 22 offspring 8 pairs responder (guinea pigs which are capable response) parents were also responders, whereas, none 26 9 non-responder responders. None 11 strain 13 and 100 40 2 These findings consistent with view that respond immunologically is genetically transmitted as a unigenic Mendelian dominant.

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