Small GTPase-regulated phospholipase D in granulocytes.
作者： Martin G. Houle , Sylvain Bourgoin
DOI: 10.1139/O96-050
关键词:
摘要: This review examines the functional role of phospholipase D in neutrophil. Phospholipase is emerging as an important component signal transduction pathways leading to granulocyte activation. Through second messenger it produces, phosphatidic acid, plays active regulation NADPH oxidase activation and granular secretion. Many factors from both cytosol membrane are necessary for maximal paper will focus on by low molecular weight GTP-binding proteins, tyrosine kinases, protein kinase C.
nrcresearchpress.com参考文章(103)
William D. Singer, H. Alex Brown, Gary M. Bokoch, Paul C. Sternweis, Resolved phospholipase D activity is modulated by cytosolic factors other than Arf. Journal of Biological Chemistry. ,vol. 270, pp. 14944- 14950 ,(1995) , 10.1074/JBC.270.25.14944
P Bellavite, F Corso, S Dusi, M Grzeskowiak, V Della-Bianca, F Rossi, Activation of NADPH-dependent superoxide production in plasma membrane extracts of pig neutrophils by phosphatidic acid. Journal of Biological Chemistry. ,vol. 263, pp. 8210- 8214 ,(1988) , 10.1016/S0021-9258(18)68464-9
P.M.C. Dang, S. Rais, J. Hakim, A. Perianin, Redistribution of protein kinase C isoforms in human neutrophils stimulated by formyl peptides and phorbol myristate acetate. Biochemical and Biophysical Research Communications. ,vol. 212, pp. 664- 672 ,(1995) , 10.1006/BBRC.1995.2020
H.Alex Brown, Stephen Gutowski, Carolyn R. Moomaw, Clive Slaughter, Paul C. Sternwels, ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity Cell. ,vol. 75, pp. 1137- 1144 ,(1993) , 10.1016/0092-8674(93)90323-I
Mark T. Quinn, LOW-MOLECULAR-WEIGHT GTP-BINDING PROTEINS AND LEUKOCYTE SIGNAL TRANSDUCTION Journal of Leukocyte Biology. ,vol. 58, pp. 263- 276 ,(1995) , 10.1002/JLB.58.3.263
D J Kusner, G R Dubyak, Guanosine 5'-[gamma-thio]triphosphate induces membrane localization of cytosol-independent phospholipase D activity in a cell-free system from U937 promonocytic leucocytes. Biochemical Journal. ,vol. 304, pp. 485- 491 ,(1994) , 10.1042/BJ3040485
K M Hurst, B P Hughes, G J Barritt, The roles of phospholipase D and a GTP-binding protein in guanosine 5′-[γ-thio]triphosphate-stimulated hydrolysis of phosphatidylcholine in rat liver plasma membranes Biochemical Journal. ,vol. 272, pp. 749- 753 ,(1990) , 10.1042/BJ2720749
R W Bonser, N T Thompson, R W Randall, L G Garland, Phospholipase D activation is functionally linked to superoxide generation in the human neutrophil. Biochemical Journal. ,vol. 264, pp. 617- 620 ,(1989) , 10.1042/BJ2640617
S Cockcroft, D Allan, THE FATTY-ACID COMPOSITION OF PHOSPHATIDYLINOSITOL, PHOSPHATIDATE AND 1,2-DIACYLGLYCEROL IN STIMULATED HUMAN-NEUTROPHILS Biochemical Journal. ,vol. 222, pp. 557- 559 ,(1984) , 10.1042/BJ2220557
J Van der Meulen, R J Haslam, Phorbol ester treatment of intact rabbit platelets greatly enhances both the basal and guanosine 5'-[gamma-thio]triphosphate-stimulated phospholipase D activities of isolated platelet membranes. Physiological activation of phospholipase D may be secondary to activation of phospholipase C. Biochemical Journal. ,vol. 271, pp. 693- 700 ,(1990) , 10.1042/BJ2710693