Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer

作者: Christine M Lovly , Nerina T McDonald , Heidi Chen , Sandra Ortiz-Cuaran , Lukas C Heukamp

DOI: 10.1038/NM.3667

关键词:

摘要: Crizotinib, a selective tyrosine kinase inhibitor (TKI), shows marked activity in patients whose lung cancers harbor fusions in the gene encoding anaplastic lymphoma receptor tyrosine …

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