Reorganization and Restoration of Central Nervous Connections after Injury: A Lesion and Transplant Study of the Rat Hippocampus

摘要: The hippocampus and fascia dentata are cortical brain structures with a distinct laminar organization of both the neuronal cell layers terminations extrinsic intrinsic afferents in neuropil. In addition, dentate granule cells among latest forming neurons brain. It has thus been estimated that rat about 85% form after birth, mainly during first postnatal days (Bayer, 1980). These structural developmental features have prompted — facilitated large number studies lesion-induced plasticity hippocampal nerve connections (see Cotman Lynch, 1976; Nadler, 1978; Zimmer, Laurberg 1980, 1981; Gall More recently these extended to include cellular connective intracerebral intraocular transplantations (Zimmer, Sunde 1981, 1983; Goldowitz et al., 1982, 1984; Kromer Zimmer Sunde, 1985).