Xenografts of mouse hippocampal tissue. Formation of nerve connections between the graft fascia dentata and the host rat brain.

作者: J. Zimmer , B. Finsen , T. Sørensen , P.H. Poulsen

DOI: 10.1016/S0079-6123(08)60293-9

关键词: Hippocampal formationFascia dentataNeuropilRat brainCholecystokininBiologyNeuroscienceCellTissue formationGraft survival

摘要: Publisher Summary This chapter discusses the formation of cross-species nerve connections in mouse hippocampal xenografts placed rat brain. The between fascia dentata and host brain appears to be regulated by same factors, which determines exchange host-graft allograft studies. conclusions on basis experimental findings: (1) surviving, intracerebral hippocampus are organotypically organized with extent according principles as allografts; (2) complete structural integration terms merging cell neuropil layers migration dentate granule cells into is common after grafting newborn recipients; (3) expression species-specific cholecystokinin (CCK) immunoreactivity mossy fiber terminals ingrowth provides a model for further studies developmental functional interactions defined groups neurons.

参考文章(40)
Jens Zimmer, Bente Finsen, Torben Sørensen, Niels Sunde, Hippocampal Transplants: Synaptic Organization, their Use in Repair of Neuronal Circuits and Mouse to Rat Xenografting Glial-Neuronal Communication in Development and Regeneration. pp. 545- 564 ,(1987) , 10.1007/978-3-642-71381-1_33
B. Finsen, P. H. Poulsen, J. Zimmer, Xenografting of fetal mouse hippocampal tissue to the brain of adult rats: effects of cyclosporin A treatment. Experimental Brain Research. ,vol. 70, pp. 117- 133 ,(1988) , 10.1007/BF00271854
B. Finsen, F. Oteruelo, J. Zimmer, Immunocytochemical characterization of the cellular immune response to intracerebral xenografts of brain tissue. Progress in Brain Research. ,vol. 78, pp. 261- 270 ,(1988) , 10.1016/S0079-6123(08)60292-7
Finn A. Geneser-Jensen, Distribution of acetyl cholinesterase in the hippocampal region of the guinea pig Cell and Tissue Research. ,vol. 124, pp. 546- 560 ,(1972) , 10.1007/BF00335257
C W Cotman, M Nieto-Sampedro, E W Harris, Synapse replacement in the nervous system of adult vertebrates. Physiological Reviews. ,vol. 61, pp. 684- 784 ,(1981) , 10.1152/PHYSREV.1981.61.3.684
Christine Gall, Nicholas Brecha, H. J. Karten, Kwen-Jen Chang, Localization of enkephalin-like immunoreactivity to identified axonal and neuronal populations of the rat hippocampus The Journal of Comparative Neurology. ,vol. 198, pp. 335- 350 ,(1981) , 10.1002/CNE.901980211
James R. West, Howard O. Nornes, Clifford L. Barnes, Martha Bronfenbrenner, The cells of origin of the commissural afferents to the area dentata in the mouse. Brain Research. ,vol. 160, pp. 203- 215 ,(1979) , 10.1016/0006-8993(79)90419-0