Insulin-like growth factor type-1 receptor transactivation in vasoactive peptide and oxidant-induced signaling pathways in vascular smooth muscle cells.
作者： Zeina M. Azar , Mohamad Z. Mehdi , Ashok K. Srivastava
DOI: 10.1139/Y06-101
关键词:
摘要: Transactivation of epidermal growth factor receptor (EGFR) is a well-documented mechanism by which vasoactive peptides and H2O2 elicit their cellular responses. However, role for the insulin-like type-1 (IGF-1R) transactivation in mediating effects angiotensin II (Ang II) vascular smooth muscle cells from different artery types have also been recently recognized. By using series pharmacological inhibitors various tyrosine kinases direct analysis phosphorylation status β-subunit IGF-1R, requirement this Ang response has demonstrated. This review discusses some studies that highlight importance IGF-1R II- H2O2-induced mitogen-activated protein kinase B signaling pathways.
nrcresearchpress.com 参考文章(49)
Jie Du, Laurence S. Sperling, Mario B. Marrero, Liz Phillips, Patrick Delafontaine, G-protein and tyrosine kinase receptor cross-talk in rat aortic smooth muscle cells: thrombin- and angiotensin II-induced tyrosine phosphorylation of insulin receptor substrate-1 and insulin-like growth factor 1 receptor. Biochemical and Biophysical Research Communications. ,vol. 218, pp. 934- 939 ,(1996) , 10.1006/BBRC.1996.0165
Juan A. Rosado, Pedro C. Redondo, Ginés M. Salido, Emilio Gómez-Arteta, Stewart O. Sage, Jose A. Pariente, Hydrogen Peroxide Generation Induces pp60srcActivation in Human Platelets Journal of Biological Chemistry. ,vol. 279, pp. 1665- 1675 ,(2004) , 10.1074/JBC.M307963200
DEREK LEROITH, HAIM WERNER, DANA BEITNER-JOHNSON, ANDCHARLES T. ROBERTS, Molecular and cellular aspects of the insulin-like growth factor I receptor Endocrine Reviews. ,vol. 16, pp. 143- 163 ,(1995) , 10.1210/EDRV-16-2-143
Fatiha Tabet, Ernesto L Schiffrin, Rhian M Touyz, Mitogen-activated protein kinase activation by hydrogen peroxide is mediated through tyrosine kinase-dependent, protein kinase C-independent pathways in vascular smooth muscle cells: upregulation in spontaneously hypertensive rats. Journal of Hypertension. ,vol. 23, pp. 2005- 2012 ,(2005) , 10.1097/01.HJH.0000185715.60788.1B
Henrik Daub, F. Ulrich Weiss, Christian Wallasch, Axel Ullrich, Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors Nature. ,vol. 379, pp. 557- 560 ,(1996) , 10.1038/379557A0
Muyao Li, Jen-Fu Chiu, Jessica Gagne, Naomi K. Fukagawa, Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells Journal of Cellular Physiology. ,vol. 217, pp. 377- 387 ,(2008) , 10.1002/JCP.21507
M. Rozakis-Adcock, J. McGlade, G. Mbamalu, G. Pelicci, R. Daly, W. Li, A. Batzer, S. Thomas, J. Brugge, P. G. Pelicci, J. Schlessinger, T. Pawson, Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature. ,vol. 360, pp. 689- 692 ,(1992) , 10.1038/360689A0
P. Delafontaine, Insulin-like growth factor I and its binding proteins in the cardiovascular system Cardiovascular Research. ,vol. 30, pp. 825- 834 ,(1995) , 10.1016/S0008-6363(95)00163-8
Satoru Eguchi, Tadashi Inagami, Signal transduction of angiotensin II type 1 receptor through receptor tyrosine kinase. Regulatory Peptides. ,vol. 91, pp. 13- 20 ,(2000) , 10.1016/S0167-0115(00)00126-9
Anna Jamroz-Wiśniewska, Grażyna Wójcicka, Ewelina Łowicka, Marta Książek, Jerzy Bełtowski, Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: Role in leptin-induced hypertension Biochemical Pharmacology. ,vol. 75, pp. 1623- 1638 ,(2008) , 10.1016/J.BCP.2008.01.003