摘要: Nach der Definition von Fredrickson und Levy (1972) ist das Syndrom Typ IV-Hyperlipoproteinamie charakterisiert durch eine Vermehrung VLDL-Lipoproteinen, die sich elektrophoretisch als Pra-β-Lipoproteine darstellen. Chylomikronen fehlen. Die vermehrten Triglyceride sind endogenen Ursprungs werden nach heutiger Kenntnis vorwiegend in Leber zu einem geringen Teil Darmmukosa aus Fettsauren synthetisiert, nicht direkt Nahrung entstammen. Konzentration bzw. VLDL-Lipoproteine im Nuchternserum meist hoher, wenn ein wesentlicher Nahrungskalorien Kohlenhydrate zugefuhrt wird („kohlenhydratinduzierte“ Hypertriglyceridamie), fettreiche Kostformen verabreicht werden.
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