Comparative effectiveness research: Relevance and applications to pharmacy.

作者: Glen T. Schumock , A. Simon Pickard

DOI: 10.2146/AJHP090150

关键词:

摘要: Purpose. An overview of the emerging field comparative effectiveness research (CER) and its relevance to pharmacists pharmacy-based decision-makers is provided. Summary. The U.S. government investing over $1 billion on CER next two years. This investment in part driven by recognition that, despite having highest per capita health care expenditures world, United States does not always perform well measures compared with other countries. There also increased awareness limited information provided results traditional randomized clinical trials inform decisions about therapeutic alternatives as applied actual practice. Comparative studies have important principal components: (1) comparison or more agents interventions that are considered true (2) examination effects (outcomes) differ from efficacy several ways, including question addressed, groups, patient population, setting, outcomes measured, validity. Studies within scope can be categorized primary secondary studies. used compare medical devices, procedures, services, any competing intervention. Conclusion. an area relevant many areas care, especially pharmacotherapy. knowledge gained when applying drug making related therapy.

参考文章(35)
Beth A Collins Sharp, Stephanie Chang, Jean Slutsky, David Atkins, Comparing Medical Interventions: AHRQ and the Effective Health Care Program Agency for Healthcare Research and Quality (US). ,(2008)
Susan Emmer, Laura Allendorf, The Medicare Prescription Drug, Improvement, and Modernization Act of 2003. Journal of the American Geriatrics Society. ,vol. 52, pp. 1013- 1015 ,(2004) , 10.1111/J.1532-5415.2004.52295.X
Jill Eden, Barbara McNeil, Ben Wheatley, Knowing What Works in Health Care: A Roadmap for the Nation ,(2008)
Writing Group for the Women's Health Initiative Investigators, Writing Group for the Women's Health Initiative Investigators, None, Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial JAMA. ,vol. 288, pp. 321- 333 ,(2002) , 10.1001/JAMA.288.3.321
Peter R. Orszag, Philip Ellis, The challenge of rising health care costs : A view from the congressional budget office The New England Journal of Medicine. ,vol. 357, pp. 1793- 1795 ,(2007) , 10.1056/NEJMP078190
Steven D. Pizer, An intuitive review of methods for observational studies of comparative effectiveness Health Services and Outcomes Research Methodology. ,vol. 9, pp. 54- 68 ,(2009) , 10.1007/S10742-009-0045-3
Arnold M. Epstein, The Outcomes Movement — Will It Get Us Where We Want to Go? New England Journal of Medicine. ,vol. 323, pp. 266- 270 ,(1990) , 10.1056/NEJM199007263230410