Mitochondrial dysfunction in breast cancer
作者： Doris Germain , Luena Papa , Timothy Kenny , Yukie Takabatake , Amanjot Kaur Riar
DOI: 10.2147/RRB.S62507
关键词:
摘要: The reprogramming of the mitochondria cancer cells is essential for their growth. However, such leads to increased formation reactive oxygen species, which can lead damage organelle. This review summarizes mechanisms that protect mitochondrial network against oxidative stress. Further, since several transcription factors have now been linked unfolded protein response (UPR mt ) and regulate expression one or more genes involved in these "mito-protective" mechanisms, UPR ), DNA, SOD2, breast cancer, mitomiRs, quality controls
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