A system for the surgical staging of musculoskeletal sarcoma.

摘要: Historically, an adequate surgical procedure has been the most effective means of treating majority primary musculoskeletal sarcomas, and amputation figured prominently in armamentarium. 4, 7, 9, 19, 21, 29, 41 The recent evidence that certain chemotherapeutic agents may have significant anti-sarcoma activity 2, 15, 17, 38 coincident technical advances irradiation therapy, radiographic localization, reconstructive surgery fostered enthusiastic interest extremity-saving treatments. Almost all such treatments emphasize limb salvage as alternative to are usually performed under a protective cloak adjunctive chemotherapy, or immunoactive agents. 20, 23, 24, 30, 37, 39 Since neither chemotherapy nor therapy alone shown assure long-term local control bulk disease, intervention remains essential step overall management sarcomas. 3, 18, 29 Questions concerning magnitude timing unanswered those relating appropriate use adjuncts themselves. Increasingly, surgeon his patient confronted with bewildering array therapeutic options, outcomes which unknown. These relatively rare sarcomas increasingly distributed among variety treatment protocols multiple parameters differ. This trend necessitates interinstitutional cooperation if sufficient numbers patients be available for timely evaluation clinical use. Such even communication seriously hampered by lack uniform language, so meaningful comparison is currently impossible. Prime factors include consistent definition serviceable staging system encompassing bone soft tissue. Standard terminology will like unlike appropriately compared. Although should serve members multidisciplinary team, biologic behavior suggests useful articulate procedure.