Selective use of PET scan in the preoperative staging of NSCLC

摘要: Abstract Positron emission tomography (PET) is a imaging technique which identifies abnormalities by utilising their metabolic properties rather than anatomical density. In this study, we evaluated the place of PET scanning for characterisation additional discovered on routine, preoperative CT evaluation patients with proven NSCLC. A total 21 underwent using fluorodeoxyglucose (FDG). these patients, routine scans had found 26 concomitant lesions were in lung, adrenal gland, liver, kidney, spleen and pleura. FDG uptake was positive at primary site all patients. 13 suggested malignancy. Malignancy confirmed foci histology eight (six thoracotomy, fine needle aspiration biopsy (FNAB) open biopsy) clinical radiological follow-up 1–15 months five. lesions, benign disease. Histology reported no evidence malignancy five six followed radiographic 2–16 falsely negative only one where thoracotomy. failed to detect remaining lesion an unassociated kidney tumour patient Li-Fraumeni syndrome. The accuracy assessment those otherwise operable NSCLC be 96% sensitivity 93% specificity 100%. These results indicate that useful characterise scan