Positron emission tomography in patients with glioma a predictor of prognosis
作者： Jane B. Alavi , Abass Alavi , John Chawluk , Michael Kushner , John Powe
DOI: 10.1002/1097-0142(19880915)62:6<1074::AID-CNCR2820620609>3.0.CO;2-H
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摘要: Positron emission tomography (PET) studies have been performed using 18-F-fluorodeoxyglucose in 29 adult subjects with primary brain tumors. Seventy-two percent of the patients were treated previously. The glucose metabolic state lesions was increased 16 patients, and normal or decreased 13 patients. hypermetabolic tumors tended to behave a more malignant fashion. Patients had median survival 7 months after PET scan, compared 33 for those hypometabolic lesions. Among high-grade glioma results separated them into good prognosis group (hypometabolic, 78% 1-year survival) poor (hypermetabolic, 29% PET). These suggest that may provide an independent measure aggressiveness tumor, supplement pathologic grading.
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