Laryngeal carcinoma and laryngo-pharyngeal reflux disease.
作者： G Almadori , G Paludetti , E De Corso , J Galli , G Cammarota
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摘要: A correlation between laryngo-pharyngeal reflux and laryngeal carcinoma is currently debated. Chronic inflammation a mutagen factor confirmed in the cancerogenesis of various tumours. Aim present study was to evaluate, an objective consecutive way, with 24h multi-electrode pH-metry presence proximal distal oesophageal patients presenting pre-cancerosis or squamous cell and/or pharyngeal carcinomas. From our data, strict emerged neoplasias upper airways, documented through pH-metry. Data emerging from this would seem support theory that protracted exposure (> 20 years) biliary represent statistically significant added risk precancerous lesions pharyngo-laryngeal as it occurs at level. Moreover, statistical association (p < 0.0001) previous gastro-resection (odds ratio 3.8).
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