Assessment of Intervention Fidelity and Recommendations for Researchers Conducting Studies on the Diagnosis and Treatment of Chronic Cough in the Adult: CHEST Guideline and Expert Panel Report

摘要: BACKGROUND Successful management of chronic cough has varied in the primary research studies reported literature. One potential reasons relates to a lack intervention fidelity core elements diagnostic and/or therapeutic interventions that were meant be used by investigators. METHODS We conducted systematic review summarize evidence supporting as an important methodologic consideration assessing effectiveness clinical practice guidelines for diagnosis and cough. developed tool assess five areas fidelity. Medline (PubMed), Scopus, Cochrane Database Systematic Reviews searched from January 1998 May 2014. Guideline recommendations suggestions those conducting using or protocols diagnose manage adult voted upon CHEST Organization methodology. RESULTS A total 23 (17 uncontrolled prospective observational, two randomized controlled, four retrospective observational) met our inclusion criteria. These articles included 3,636 patients. Data could not pooled meta-analysis because heterogeneity. Findings related three primarily provider In area study design , 11 appeared underpinned single guideline/protocol; training providers training, zero use manual; delivery treatment when gastroesophageal reflux disease, consistent with most recent guideline/protocol referenced authors. For receipt mentioned measuring concordance patient-interventionist understanding recommended, enactment side effects adherence. The overall average score all was poor (20.74 out 48). CONCLUSIONS Only low-quality supports strategies diagnosing managing adults. This contention some variability reporting patients unexplained unresolved may due By following this article, researchers will likely better able incorporate address fidelity, thereby strengthening validity generalizability their results provide basis development trustworthy guidelines.