Die kardiale Resynchronisationstherapie bei terminaler Herzinsuffizienz

作者: Heiner Wieneke , Raimund Erbel , Frank Heinzel , Nikolaos Dagres , Stefan Sack

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摘要: Hintergrund: Die Herzinsuffizienz zeigt unter epidemiologischen Aspekten eine zunehmende Inzidenz, wahrend fur die koronare Herzerkrankung durch Sekundar- und Primarpravention ein zahlenmasiger Ruckgang festzustellen ist. Nach den vorliegenden Daten ist mit einer Pravalenz von 2% pro Jahr zu rechnen. Das bedeutet 4–5 Mio. Neuerkrankungen jahrlich. Prognose nach Diagnosestellung erheblich limitiert. der US-amerikanischen Framingham-Studie liegt mediane Lebenserwartung Manner bei 3,2 Frauen 5,4 Jahren Diagnosestellung. Fur Patienten fortgeschrittener steigt Mortalitatsrate auf 27% in drei Jahren. AV-sequenzielle Stimulation: Einfuhrung AV-sequenziellen Stimulation osterreichische Arbeitsgruppe Margarete Hochleitner 1992 zeigte vorhofgetriggerten des rechten Ventrikels Verbesserung myokardialen Funktion, Ausdruck fand betrachtlichen klinischen um zwei Stufen NYHAKlassifikation, Zunahme linksventrikularen Ejektionsfraktion, systolischen diastolischen Blutdrucks, Abnahme Herz-Thorax-Qutienten, Herzfrequenz sowie echokardiographischen Dimensionsparameter. Studien: Erste experimentelle Studien zur biventrikularen Stimulation, das heist synchronen Aktivierung rechCardiac Resynchronization Therapy (CRT) – a New Option the Treatment of End-Stage Heart Failure Background: With regard to epidemiological aspects, heart failure has been shown an increasing incidence constrast coronary artery disease which counts decreasingly due secondary and primary prevention. The present data show for per year. 4 5 million people are newly affected by disease. prognosis is limited after diagnosis confirmed. According US Framingham study, median life expectancy 3.2 5.4 male female, respectively. For patients advanced stage mortality rate within 3 years. AV Sequential Pacing: introduction sequential pacing Austrian group showed improved left ventricular systolic function, clinical benefit terms NYHA classification, enhanced ejection fraction, diastolic blood pressure, reduction heart-chest reSchlusselworter: · Herzschrittmacher Resynchronisationstherapie Hamoydnamik

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