Higher Body Mass Index Increases the Risk for Biopsy-Mediated Detection of Prostate Cancer in Chinese Men

摘要: Objective To investigate the relationship between body mass index (BMI) and prostate cancer (PCa) risk at biopsy in Chinese men. Patients Methods We retrospectively reviewed records of 1,807 consecutive men who underwent initial multicore (≥10) under transrectal ultrasound guidance Dec 2004 Feb 2014. BMI was categorised based on Asian classification obesity as follows: <18.5 (underweight), 18.5–22.9 (normal weight), 23–24.9 (overweight), 25–29.9 (moderately obese), ≥30 kg/m2 (severely obese). The odds ratios (OR) each category for PCa high-grade (HGPCa, Gleason score ≥4+3) detection were estimated crude, age-adjusted multivariate-adjusted models. Prevalence accuracies PSA predicted also across groups. Results In total, detected by 750 (45.4%) men, HGPCa 419 (25.4%) men. Compared with normal weight, underweight obese older had higher specific antigen levels. overall via presented an obvious U-shaped crude analysis. Overall, 50.0%, 37.4%, 45.6% 54.4% 74.1% underweight, overweight, moderately severely groups, respectively, diagnosed biopsy. In multivariate analysis, significantly correlated a (OR = 1.17, 95%CI 1.10–1.25, P<0.001). However, not 1.03, 0.97–1.09, P 0.29). There no significant differences accuracy using to predict or different categories. Conclusion Obesity associated present population. No association HGPCa.