Icariin inhibits osteoclast differentiation and bone resorption by suppression of MAPKs/NF-κB regulated HIF-1α and PGE(2) synthesis.
作者： Tsai-Pei Hsieh , Shiow-Yunn Sheu , Jui-Sheng Sun , Ming-Hong Chen
DOI: 10.1016/J.PHYMED.2010.04.003
关键词:
摘要: … Lipopolysaccharide can enhance ACP/TRAP synthesis, while icariin can inhibit LPS-induced osteoclastogenesis through suppressing the synthesis of ACP and TRAP (n = 4, Fig. 2A …
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