Review of current blood transfusions strategies in a mature level I trauma center: were we wrong for the last 60 years?
作者： Juan C. Duchesne , John P. Hunt , Georgia Wahl , Alan B. Marr , Yi-Zarn Wang
DOI: 10.1097/TA.0B013E31817E5166
关键词:
摘要: analysis. The primary research question was the impact of initial FFP:PRBC ratio on mortality. Other variables for analysis included patient age, gender, mechanism, and Injury Severity Scale score. Both univariate multivariate were used to assess relationship between outcome predictors. Results: A total 2,746 patients underwent surgical intervention which 1,985 (72.2%) received no transfusion. Of those that transfusion, 626 (22.8%) 10 units PRBC. Out PRBC FFP. In analysis, a significant difference in mortality found who >10 (26% vs. 87.5%) when 1:1 versus 1:4 (p 0.0001). Multivariate group showed consistent with increased risk (relative risk, 18.88; 95% CI, 6.32–56.36; p 0.001), compared 1:1. Patients <10 had trend toward (21.2% vs.11.8%) (p: 0.06).
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