摘要: Genetic intersectional strategies were employed to exclude GABAergic neurons from the 5HT-1B+/fru+ neurons. Either silencing or activating 5HT-1B+/ fru+/GAD− did not produce disinhibition aggression phenotype. These results suggest that perhaps only 5-HT1B+/fru+/GAD+ triple positive are essential for suppressing male–male by female contact. Finally, authors discovered type A GABA receptor, Resistant dieldrin (RDL), was involved in inhibiting prior Acute activation of RDL+/fru+ increased aggression, indicating an aggression-promoting role these Taken together, suppress male downstream It would be interesting directly label and manipulate those 5HT1B+/fru+ examine behavioral consequences. This study opens a new avenue explore how sexual experience modulates aggressive behavior identifies set neural circuits this process. remains elucidated pheromone signals relayed ppk29 For example, sensitive pheromones? The RDL+ remain clearly defined functional connectivity between needs characterized. Most interestingly, what is mechanism underlying temporal transition promoting acute contact chronic contact? An understanding mediate social modulation on flies may shed insights into basis human violence.