Are We Choosing Wisely With Autologous Hematopoietic Cell Transplantation Screening? The Utility of Pulmonary Function Testing Prior to Autologous Hematopoietic Cell Transplantation

摘要: Abstract Introduction Despite the risk of morbidity and mortality associated with autologous hematopoietic cell transplantation (ASCT), there are no clear guidelines as to how screen for these risks. This study sought determine utility pulmonary function tests (PFTs) prior ASCT on predicting posttransplant clinical outcomes. Patients Methods undergoing between 2010 2012 at Ottawa Hospital (n = 172) were reviewed. PFT results retrieved. The primary outcomes incidence intensive care unit (ICU) admission, Seattle Criteria toxicities, transplant-related (TRM). Results PFTs performed 91 (53%) patients ASCT. There more smokers in cohort than non-PFT (41.8% vs. 19.8%, respectively; P  Conclusion testing deemed higher toxicity, abnormal did not predict an increased ICU or TRM our center.