Sodium Ions in the Electromechanical Coupling System of Myocardium and Skeletal Muscles of the Frog Rana temporaria

摘要: The role of the transsarcolemmal Na+ gradient in providing phasic contraction myocardium and skeletal muscles common frog Rana temporaria was studied. It shown that a decrease by means total or partial substitution for Ch+ Li+ produced tissue-specific reduction isometric tension developed as well maximum rate its development. functional mechanisms use Na+-gradient intracellular mobilization activator muscle contraction, Ca2+ ions, are considered, experimental evidences significance this increase to provide intensification process activation discrete (single, rhythmic) vertebrate presented. revealed differences between studied reflect adaptive rearrangement levels ionic electromechanical coupling system these muscles, which achieved course evolution their contractile function.