Clinical significance of ascites in epithelial ovarian cancer.

摘要: The prognostic significance of ascites in the dissemination metastases epithelial ovarian cancer (EOC) is unclear. Our study aimed to investigate association between clinicopathological factors and development ascites, as well its significance. Three hundred thirty three patients with primary EOC were suitable for inclusion. We analyzed correlation factors, including extent metastases, ascitic volume. was assessed using Kaplan-Meier method multivariate Cox's regression analysis. average volume 1,800 ml. Significantly, more advanced FIGO stage disease presented ascites. increased significantly when metastatic present than regions (p<0.05), this sole factor identified associated by multiple linear Median survival different those an less ml (median = 58 months), a greater 28.6 months) (p<0.05). Subgroup analysis III IV also revealed poor prognosis presence massive (p 0.03). Multivariate analyses found that differentiation independent Cox regression, backward elimination procedure. metastastic disease. Massive tumor worse cancer.