Simple, distance-based measurement for paper analytical devices

摘要: Paper-based analytical devices (PADs) represent a growing class of elegant, yet inexpensive chemical sensor technologies designed for point-of-use applications. Most PADs, however, still utilize some form instrumentation such as camera quantitative detection. We describe here simple technique to render PAD measurements more and straightforward using the distance colour development detection motif. The so-called distance-based enables chemistries that are portable less resource intensive compared classical approaches rely on use peripheral equipment measurement. demonstrate utility broad applicability this with glucose, nickel, glutathione three different chemistries: enzymatic reactions, metal complexation, nanoparticle aggregation, respectively. results show excellent agreement certified standards in complex sample matrices. This work provides first demonstration application new,