Electrochemical decarboxylative C3 alkylation of quinoxalin-2(1H)-ones with N-hydroxyphthalimide esters.
作者： Kaikai Niu , Lingyun Song , Yanke Hao , Yuxiu Liu , Qingmin Wang
DOI: 10.1039/D0CC05391K
关键词:
摘要: We have developed a protocol for electrochemical decarboxylative C3 alkylation of wide range quinoxalin-2(1H)-ones under metal- and additive-free conditions. N-Hydroxyphthalimide esters derived from chain, cyclic, primary, secondary, tertiary carboxylic acids with broad scope proved to be suitable substrates. This operationally simple performed in an undivided cell constant-current conditions is late-stage functionalization quinoxalin-2(1H)-ones. The reactions can even carried out 3 V battery as power source, which demonstrates that organic electrosynthesis accomplished without the need specialized equipment.
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