A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells
作者： Michel Weïwer , James Spoonamore , Jingqiang Wei , Boris Guichard , Nathan T. Ross
DOI: 10.1021/ML300246R
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摘要: … to STK33. For example, 1 is 2-fold selective for Aurora-B (AurB) versus STK33, and 2 is only ∼5-fold selective for STK33 … the correlation between the STK33 activity and the observed …
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