Meta-analysis of pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy.

摘要: Background: Pancreaticoduodenectomy is the primary treatment for periampullary cancer. Associated morbidity high and often related to pancreatic anastomotic failure. This paper compares rates of fistula, mortality after pancreaticoduodenectomy in patients having reconstruction by pancreaticogastrostomy with those pancreaticojejunostomy. Methods: Am eta-analysis was performed all large cohort randomized controlled trials carried out since 1990. Results: Eleven articles were identified inclusion: one prospective trial, two nonrandomized eight observational studies. The meta-analysis revealed a higher rate fistula associated pancreaticojejunostomy (relative risk (RR) 2·62 (95 per cent confidence interval (c.i.) 1·91 3·60)). A overall also demonstrated this group (RR 1·43 c.i. 1·26 1·61)), as 2·51 1·61 3·91)). Conclusion: Current literature suggests that safer means pancreaticogastrostomy, but much evidence comes from study data.