Nucleic acids encoding modulators of body weight

摘要: The present invention relates generally to the control of body weight animals including mammals and humans, more particularly nucleic acids encoding materials identified herein as modulators weight. In its broadest aspect, elucidation discovery nucleotide sequences, proteins putatively expressed by such nucleotides, that demonstrate ability participate in mammalian sequences object represent genes corresponding murine human ob gene, have been postulated play a critical role regulation adiposity. Preliminary data, presented herein, suggests polypeptide product gene question functions hormone. further provides acid molecules for use molecular probes, or primers polymerase chain reaction (PCR) amplification, i.e., synthetic natural oligonucleotides.