Synergistic inhibition of the growth in vitro of Microsporum canis by miconazole and chlorhexidine.

摘要: An agar dilution technique was used to assess the minimum inhibitory concentrations (MIC) of miconazole, chlorhexidine and a 1:1 combination both agents for 10 isolates Microsporum canis. For nine isolates, miconazole more effective than either agent alone; fractional concentration indices indicated synergistic effect five an additive four. These results illustrate potent antimycotic against M. canis are in accordance with previous clinical studies that showed value using shampoo association oral griseofulvin treatment feline dermatophytosis caused by