作者: M.M. Garcia Basalo , M.C. Fernandez , M. Ojea Quintana , J.I. Rojas , M.J. Garcia Basalo
DOI: 10.1016/J.ARCHGER.2017.01.001
关键词:
摘要: Abstract Background Early detection of neurodegenerative diseases is essential for treatment and proper care these patients. Screening tools available today are effective several types dementia. However, there no one specific Lewy Body Dementia (LBD). Objectives The aim this paper to present a tool early LBD, accessible even non-medical staff. Methods We stratified subjects (MMSE > 20) into four groups: health controls (HC), Mild Cognitive Impairment (MCI), LBD other dementias (Alzheimer vascular). All (age range 50–90) were examined with comprehensive neuropsychological neuropsychiatric evaluation, as well neuroimaging differentiate diagnosis between groups, fulfilling corresponding criteria. Both neurologists neuropsychologists blind the performance on clinical evaluations ASI, respectively. sensitivity specificity instrument determined from groups. Results evaluated 427 subjects, 91 HC, 140 MCI 196 In dementia group, 75 diagnosed 121 dementias. ASI total score was 12.7 ± 0.4 2.9 ± 0.2 5 ± 0.7 MCI, 5.4 ± 2.6 causes ROC curve analysis showed 90.7% 93.6% stands, 9 cutoff better test compared against Conclusion brief screening high useful