Wound healing following regenerative procedures in furcation degree III defects: histomorphometric outcomes.
作者： Nikolaos D. Gkranias , Filippo Graziani , Anton Sculean , Nikolaos Donos
DOI: 10.1007/S00784-010-0478-7
关键词:
摘要: Degree III furcation involvements were surgically created at four first molars in each of three monkeys. Following 6 weeks healing, full-thickness flaps elevated. 24% EDTA gel conditioning, the defects treated with one following: (1) enamel matrix proteins (EMD), (2) guided tissue regeneration (GTR) or (3) a combination EMD and GTR. The control did not receive any treatment. After 5 months animals sacrificed. Three 8 μm thick histological central sections, 100 apart, used for histomorphometric analysis six zones tooth either within area on pristine external surface root. In all specimens, new cementum inserting collagen fibres was formed. GTR + EMD, formed up to including fornix indicating complete defect periphery. Periodontal ligament less modalities compared tissues. teeth higher volume bone periodontal tissues observed EMD. regenerated presented quantitative differences from two where alone combined used, differed quantity EMD-treated sites.
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