Recent Patents and Emerging Therapeutics in the Treatment of Allergic Conjunctivitis
作者： Gyan P Mishra , Viral Tamboli , Jwala Jwala , Ashim K Mitra , None
DOI: 10.2174/187221311794474883
关键词:
摘要: Ocular allergy is an inflammatory response of the conjunctival mucosa that also affects cornea and eyelids. Allergic conjunctivitis includes seasonal allergic (SAC), perennial (PAC), vernal keratoconjunctivitis (VKC), atopic (AKC) giant papillary (GPC). In general, conditions involve mast cell degranulation leads to release mediators activation enzymatic cascades generating pro-inflammatory mediators. chronic ocular disorders associated with such as VKC AKC constant observed due predominance eosinophils Th2-generated cytokines. Antihistamines, mast-cell stabilizers, nonsteroidal anti-inflammatory agents, corticosteroids immunomodulatory agents are commonly indicated for treatment acute conjunctivitis. recent years newer drug molecules have been introduced in This article reviews patents emerging therapeutics
eurekaselect.com
researchgate.net 参考文章(76)
John M. Yanni, Daniel A. Gamache, Steven T. Miller, Clay Beauregard, Use of a combination of olopatadine and cilomilast to treat non-infectious rhinitis and allergic conjunctivitis ,(2009)
John M. Yanni, Daniel A. Gamache, Jon E. Chatterton, Steven T. Miller, RNAi-Mediated Inhibition of Histamine Receptor H1-Related Conditions ,(2007)
John M. Yanni, Daniel A. Gamache, Allen J. Borchardt, Clay Beauregard, Robert L. Davis, Aminopyrimidine inhibitors of histamine receptors for the treatment of disease ,(2009)
Clay Beauregard, Peter G. Klimko, Method of treating ocular allergy ,(2010)
John M. Yanni, Daniel A. Gamache, Jon E. Chatterton, Steven T. Miller, RNAi-MEDIATED INHIBITION OF SPLEEN TYROSINE KINASE-RELATED INFLAMMATORY CONDITIONS ,(2007)
Stewart A. Noble, David J. Thomas, Steven P. Govek, Andrew K. Shiau, Bicyclic heteroaryl inhibitors of pde4 ,(2007)
Rong-Tsun Wu, Method for treating allergic diseases ,(2008)
Rosaliz Portela, Salim Butrus, Ocular Allergy: Diagnosis and Treatment Ophthalmology Clinics of North America. ,vol. 18, pp. 485- 492 ,(2005) , 10.1016/J.OHC.2005.07.007
Avner Ingerman, Frans Janssens, Anton Megens, Jagdish Parasrampuria, Ocular allergy treatments ,(2007)
A. W. FRANKLAND, S. R. WALKER, A clinical comparison of topical clobetasone butyrate and sodium cromoglycate in allergic conjunctivitis. Clinical & Experimental Allergy. ,vol. 11, pp. 473- 478 ,(1981) , 10.1111/J.1365-2222.1981.TB01621.X