摘要: In this issue of Cell Reports, Van den Bossche et al. (2016) reveal that, once the M1 macrophage forms, accompanying metabolic alterations in mitochondria are irreversible, preventing differentiation into more homeostatic M2 macrophage.
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edepositireland.ie参考文章(11)
Luke AJ O’Neill, Silvia Galvan-Penal, Metabolic Reprograming in Macrophage Polarization Frontiers in Immunology. ,vol. 5, pp. 420- 420 ,(2014) , 10.3389/FIMMU.2014.00420
Abhishek K. Jha, Stanley Ching-Cheng Huang, Alexey Sergushichev, Vicky Lampropoulou, Yulia Ivanova, Ekaterina Loginicheva, Karina Chmielewski, Kelly M. Stewart, Juliet Ashall, Bart Everts, Edward J. Pearce, Edward M. Driggers, Maxim N. Artyomov, Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization. Immunity. ,vol. 42, pp. 419- 430 ,(2015) , 10.1016/J.IMMUNI.2015.02.005
G. M. Tannahill, A. M. Curtis, J. Adamik, E. M. Palsson-McDermott, A. F. McGettrick, G. Goel, C. Frezza, N. J. Bernard, B. Kelly, N. H. Foley, L. Zheng, A. Gardet, Z. Tong, S. S. Jany, S. C. Corr, M. Haneklaus, B. E. Caffrey, K. Pierce, S. Walmsley, F. C. Beasley, E. Cummins, V. Nizet, M. Whyte, C. T. Taylor, H. Lin, S. L. Masters, E. Gottlieb, V. P. Kelly, C. Clish, P. E. Auron, R. J. Xavier, L. A. J. O’Neill, Succinate is an inflammatory signal that induces IL-1β through HIF-1α Nature. ,vol. 496, pp. 238- 242 ,(2013) , 10.1038/NATURE11986
E. Clementi, G. C. Brown, M. Feelisch, S. Moncada, Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 7631- 7636 ,(1998) , 10.1073/PNAS.95.13.7631
Eva M. Palsson-McDermott, Anne M. Curtis, Gautam Goel, Mario A.R. Lauterbach, Frederick J. Sheedy, Laura E. Gleeson, Mirjam W.M. van den Bosch, Susan R. Quinn, Raquel Domingo-Fernandez, Daniel G.W. Johnston, Jian-kang Jiang, William J. Israelsen, Joseph Keane, Craig Thomas, Clary Clish, Matthew Vander Heiden, Ramnik J. Xavier, Luke A.J. O’Neill, Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages Cell Metabolism. ,vol. 21, pp. 65- 80 ,(2015) , 10.1016/J.CMET.2014.12.005
Peter J. Murray, Judith E. Allen, Subhra K. Biswas, Edward A. Fisher, Derek W. Gilroy, Sergij Goerdt, Siamon Gordon, John A. Hamilton, Lionel B. Ivashkiv, Toby Lawrence, Massimo Locati, Alberto Mantovani, Fernando O. Martinez, Jean-Louis Mege, David M. Mosser, Gioacchino Natoli, Jeroen P. Saeij, Joachim L. Schultze, Kari Ann Shirey, Antonio Sica, Jill Suttles, Irina Udalova, Jo A. van Ginderachter, Stefanie N. Vogel, Thomas A. Wynn, Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines Immunity. ,vol. 41, pp. 14- 20 ,(2014) , 10.1016/J.IMMUNI.2014.06.008
Vicky Lampropoulou, Alexey Sergushichev, Monika Bambouskova, Sharmila Nair, Emma E. Vincent, Ekaterina Loginicheva, Luisa Cervantes-Barragan, Xiucui Ma, Stanley Ching-Cheng Huang, Takla Griss, Carla J. Weinheimer, Shabaana Khader, Gwendalyn J. Randolph, Edward J. Pearce, Russell G. Jones, Abhinav Diwan, Michael S. Diamond, Maxim N. Artyomov, Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation Cell Metabolism. ,vol. 24, pp. 158- 166 ,(2016) , 10.1016/J.CMET.2016.06.004
Johan Garaude, Rebeca Acín-Pérez, Sarai Martínez-Cano, Michel Enamorado, Matteo Ugolini, Estanislao Nistal-Villán, Sandra Hervas-Stubbs, Pablo Pelegrin, Leif E Sander, José A Enríquez, David Sancho, None, Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense Nature Immunology. ,vol. 17, pp. 1037- 1045 ,(2016) , 10.1038/NI.3509
Lara Szewczak, When a Stomach Bug Comes Calling Cell. ,vol. 167, pp. 1- 3 ,(2016) , 10.1016/J.CELL.2016.09.019
Evanna L. Mills, Beth Kelly, Angela Logan, Ana S.H. Costa, Mukund Varma, Clare E. Bryant, Panagiotis Tourlomousis, J. Henry M. Däbritz, Eyal Gottlieb, Isabel Latorre, Sinéad C. Corr, Gavin McManus, Dylan Ryan, Howard T. Jacobs, Marten Szibor, Ramnik J. Xavier, Thomas Braun, Christian Frezza, Michael P. Murphy, Luke A. O’Neill, Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages Cell. ,vol. 167, pp. 457- 470 ,(2016) , 10.1016/J.CELL.2016.08.064