Toxic oil syndrome: A syndrome with features overlapping those of various forms of scleroderma

摘要: Abstract Thirty-two toxic oil syndrome (TOS) patients were selected because they presented with sclerodermalike changes and observed during the first 36 months of evolution disease. Initially, these a noncardiogenic pulmonary edema, eosinophilia, arthralgia/arthritis, peripheral myositis. Histologic investigations showed widespread chronic interstitial infiltrate lymphocytic vasculitis. They subsequently developed neuropathy, joint contractures, scleroderma-like changes, Raynaud phenomenon, hypertension, sicca syndrome, liver Biopsy studies this stage fibrosis obliterating arteriopathy. Late features TOS are musculoskeletal pain, cramps, livedo reticularis. carpal tunnel digital tuft changes. is new chemically induced overlapping those eosinophilic fasciitis, systemic sclerosis, forms localized scleroderma.