The role of palmitoylation in regulating Ras localization and function.
作者： Sharon Eisenberg , Alex J. Laude , Alison J. Beckett , Craig J. Mageean , Veronica Aran
DOI: 10.1042/BST20120268
关键词:
摘要: Ras GTPases are important regulators of pathways controlling proliferation, differentiation and transformation. Three ubiquitously expressed almost identical genes not functionally redundant; this has been attributed to their distinctive trafficking localization profiles. A palmitoylation cycle controls the correct compartmentalization H-Ras N-Ras. We review recent data that reveal how can be regulated by membrane organization influence spatiotemporal signalling Ras.
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biochemsoctrans.org参考文章(39)
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