Physical Determinants of Vitamin D Photosynthesis: A Review

摘要: Vitamin D synthesis by exposure of skin to solar ultraviolet radiation (UVR) provides the majority this hormone that is essential for bone development and maintenance but may be important many other health outcomes. This process, which only well-established benefit UVR exposure, depends on factors including genetics, age, health, behavior. However, most factor quantity quality reaching skin. specifically requires B (UVB) minority component (<5%) UVR. waveband also adverse effects exposure. The obvious sunburn (erythema), UVB main cause DNA damage a prerequisite cancers. at Earth's surface physical temporal such as latitude, altitude, season, weather. Personal, cultural, behavioral are important. These include melanin, clothing, body area exposed, holiday habits, sunscreen use. There considerable disagreement in literature about role some these factors, possibly because studies have been done researchers with little understanding photobiology. It can argued vitamin supplementation obviates need shown from approach wide range increasing evidence offers benefits independently D: blood-pressure reduction. In any case, public advice must optimize risk versus fortunate individual doses necessary maintaining optimal status lower than those sunburn, irrespective melanin. © 2020 Authors. JBMR Plus published Wiley Periodicals LLC. behalf American Society Bone Mineral Research.