Aeromonas associated diarrhoeal disease in south Brazil: prevalence, virulence factors and antimicrobial resistance

摘要: Aeromonas were isolated from 27 (6.6%) of 408 patients admitted with acute gastroenteritis in two hospitals at Rio Grande do Sul, Brazil. Isolates classified as A. hydrophila (51.8%), caviae (40.8%), and veronii biotype sobria (7.4%). The highest prevalence associated infections occurred lactants children. Virulence genes (aerA -aerolysin/hemolysin, ahpA -serine-protease, satA - glycerophospholipid-cholesterol acyltransferase, lipA -lipase, ahyB -elastase) virulence factors (hemolytic, proteolitic, lipolitic activities, biofilm formation) identified most isolates, lower frequencies on caviae. All isolates resistant to ampicillin, ticarcillin/clavulanic acid, cephalotin, cephazolin, them (>70%) exhibited resistance imipenem, carbenicillin, amoxillin/sulbactan, piperacillin. Multiple-resistance, more than four antibiotics, was evidenced 29.6% the isolates. efficient antibiotics quinolones (ciprofloxacin norfloxacin), aminoglycosides (amikacin netilmicin).