Cytokeratin expression patterns for distinction of odontogenic keratocysts from dentigerous and radicular cysts

摘要: BACKGROUND The clinical outcome of treatment odontogenic cysts differs depending on separate entities. Particular relevance must be attached to the distinction between keratocysts, which have an evident tendency recur, and other cysts. aim this study was evaluate cytokeratin (CK) expression patterns as additional tool for characterization different histomorphologic appearance often is not decisive. METHODS Thirty cases dentigerous radicular respectively well 15 keratocysts were considered. Expression CK 5/6, 7, 10, 13, 17, 19 20 determined in addition Ki-67 immunohistochemically. RESULTS 17 discernible 93.3% but only 35.0% under (P < 0.001). could detected 48.3% cysts, whereas completely negative 0.002). CONCLUSION Immunohistochemical detection seems a valuable parameter distinguishing odontogenic--especially dentigerous--cysts clinically are likely most significant differential diagnoses context. J Oral Pathol Med (2005) 34: 558-64.