Hepatic fat, not visceral fat, is associated with gallbladder polyps: a study of 2643 healthy subjects.

摘要: Background and Aim Gallbladder polyps (GBPs) appear to be strongly associated with obesity metabolic disease. To date, the relationship between GBPs fatty liver has not been adequately evaluated. The aim of present study was investigate whether are liver, which is an ectopic regional fat deposit, independent visceral adipose tissue (VAT). Methods A cross-sectional using 2643 health checkup subjects (961 patients GBP 1682 age- sex-matched healthy controls) conducted. underwent various laboratory tests, abdominal computed tomography (CT), hepatic ultrasonography. Results The mean age 51.4 ± 8.3 years, 74.1% were male. significantly liver. Multivariate regression analysis revealed that presence (odds ratio [OR] 1.23, 95% confidence interval [CI]: 1.02–1.48), adjusting for homeostatic assessment index had little effect on this association (OR CI: 1.02–1.48). Additionally, remained after adjustments CT-measured VAT subcutaneous 1.24, 1.03–1.50). degree showed 1.37 1.03–1.80) dose-dependent (moderate-severe liver: OR 1.55 1.07–2.23, P trend = 0.014) large (≥ 5 mm). Conclusion Fatty found closely known risk factors, insulin resistance, VAT, confirming a relevant clinical two diseases.