Spherically agglomerated starches with silicon dioxide

作者: Saiyavit Varavinit , Aupakit Wongsuragrai , Varatus Wongsuragrai

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摘要: Granules of starch or low protein rice flour are agglomerated to a larger size and spherical shape by combining the granules with silicon dioxide water form slurry, drying slurry spray dryer. The agglomerates have better flowability than granules, readily used as direct compression fillers for tablets capsules in drug nutrient formulations. Tablets formed from these good hardness friability, well favorable disintegration dissolution characteristics. Chemically physically modified starches can also be used, other included well.